Chemotherapy Induced Alopecia and Scalp cooling Methods: A review of literature
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Abstract
Chemotherapy-induced alopecia (CIA) is one of the side effects of chemotherapy that is the most traumatic aspect of treatment for more than half of the patients. CIA is associated with increased psychosocial stress regarding body image, self-esteem, and sexuality. It is estimated that 60-85% of individuals who received chemotherapy treatment for cancer experienced some degree of CIA. Various techniques have been used to prevent CIA, including scalp compression, scalp cooling, and medical treatments. Herein, we provide a review of scalp cooling methods, advantages and disadvantages, requirements, and related papers.
1. Batchelor D. Hair and cancer chemotherapy: consequences and nursing care–a literature study. Eur J Cancer. 2001;10(3):147-63.
2. Choi EK, Kim IR, Chang O, et al. Impact of chemotherapy‐induced alopecia distress on body image, psychosocial well‐being, and depression in breast cancer patients. Psycho Oncol. 2014;23(10):1103-10.
3. Macquart-Moulin G, Viens P, Bouscary M, Genre D, et al. Discordance between physicians' estimations and breast cancer patients' self-assessment of side-effects of chemotherapy: an issue for quality of care. Br J Cancer. 1997;76(12):1640-5.
4. Hilton S, Hunt K, Emslie C, Salinas M, Ziebland S. Have men been overlooked? A comparison of young men and women's experiences of chemotherapy‐induced alopecia. Psycho Oncol. 2008;17(6):577-83.
5. Wang J, Lu Z, Au JL-S. Protection against chemotherapy-induced alopecia. Pharm Res. 2006;23(11):2505-14.
6. Kruse M, Abraham J. Management of chemotherapy-induced alopecia with scalp cooling. J Oncol Pract. 2018;14(3):149-54.
7. Aygin D, Aysel G. Scalp Hypothermia (Penguin Cold Caps) in Preventing Alopecia in Cancer Patients. Turk J Oncol. 2020;35(2):225–36.
8. Fairlamb D. Hair changes following cytotoxic drug induced alopecia. Postgrad Med J. 1988;64(757):907.
9. Shah VV, Wikramanayake TC, DelCanto GM, et al. Scalp hypothermia as a preventative measure for chemotherapy‐induced alopecia: a review of controlled clinical trials. J Eur Acad dermatol Venereol. 2018;32(5):720-34.
10. Shin H, Jo SJ, Kim DH, Kwon O, Myung SK. Efficacy of interventions for prevention of chemotherapy‐induced alopecia: A systematic review and meta‐analysis. Int J Cancer. 2015;136(5):E442-E54.
11. Haque E, Alabdaljabar MS, Ruddy KJ, et al. Management of chemotherapy-induced alopecia (CIA): a comprehensive review and future directions. Crit Rev Oncol Hematol. 2020;156:103093.
12. Pires EM, Pinheiro RR, Lencastre A. Alopécia Permanente Pós-Quimioterapia com Resposta Favorável ao Minoxidil Tópico. Port J Derm & Venereol . 2017;75(3):297-9.
13. Phillips GS, Freret ME, Friedman DN, et al. Assessment and treatment outcomes of persistent radiation-induced alopecia in patients with cancer. JAMA Dermatol. 2020;156(9):963-72.
14. Freites-Martinez A, Shapiro J, van den Hurk C, et al. Persistent chemotherapy-induced alopecia, persistent radiotherapy-induced alopecia, and hair growth disorders related to endocrine therapy or cancer surgery. J Am Acad Dermatol. 2019;80(5):1199.
15. Fischer TW, Trüeb RM, Hänggi G, Innocenti M, Elsner P. Topical melatonin for treatment of androgenetic alopecia. Int J Trichology. 2012;4(4):236.
16. Bussoletti C, Tolaini MV, Celleno L. Efficacy of a cosmetic phyto-caffeine shampoo in female androgenetic alopecia. G Ital Dermatol Venereol. 2018;155(4):492-9.
17. D’Agostini F, Fiallo P, Ghio M, De Flora S. Chemoprevention of doxorubicin-induced alopecia in mice by dietary administration of L-cystine and vitamin B6. Arch Dermatol Res. 2013;305(1):25-34.
18. Sharquie KE, Al‐Obaidi HK. Onion juice (Allium cepa L.), a new topical treatment for alopecia areata. J Dermatol. 2002;29(6):343-6.
19. Dąbrowski T. Hair loss as a consequence of cancer chemotherapy–physical methods of prevention. A review of the literature. Contemp Oncol. 2011;15(2):95-101.
20. Katsimbri P, Bamias A, Pavlidis N. Prevention of chemotherapy-induced alopecia using an effective scalp cooling system. Eur J Cancer. 2000;36(6):766-71.
21. Marks DH, Okhovat J-P, Hagigeorges D, et al. The effect of scalp cooling on CIA-related quality of life in breast cancer patients: a systematic review. Breast Cancer Res Treat. 2019;175:267-76.
22. Kadakia KC, Rozell SA, Butala AA, Loprinzi CL. Supportive cryotherapy: a review from head to toe. J Pain Symptom Manage. 2014;47(6):1100-15.
23. Grevelman E, Breed W. Prevention of chemotherapy-induced hair loss by scalp cooling. Ann Oncol. 2005;16(3):352-8.
24. Dunnill CJ, Al‐Tameemi W, Collett A, Haslam IS, Georgopoulos NT. A clinical and biological guide for understanding chemotherapy‐induced alopecia and its prevention. Oncologist. 2018;23(1):84-96.
25. Rugo HS, Klein P, Melin SA, et al. Association between use of a scalp cooling device and alopecia after chemotherapy for breast cancer. JAMA. 2017;317(6):606-14.
26. Nangia J, Wang T, Osborne C, et al. Effect of a scalp cooling device on alopecia in women undergoing chemotherapy for breast cancer: the SCALP randomized clinical trial. JAMA. 2017;317(6):596-605.
27. Van den Hurk CJ, Peerbooms M, van de Poll-Franse LV, Nortier JW, Coebergh JWW, Breed WP. Scalp cooling for hair preservation and associated characteristics in 1411 chemotherapy patients-results of the Dutch Scalp Cooling Registry. Acta Oncol. 2012;51(4):497-504.
28. Forsberg S. Scalp cooling therapy and cytotoxic treatment. Lancet.2001;357(9262):1134.
29. Lemieux J, Amireault C, Provencher L, Maunsell E. Incidence of scalp metastases in breast cancer: a retrospective cohort study in women who were offered scalp cooling. Breast Cancer Res Treat. 2009;118(3):547-52.
30. Rugo HS, Melin SA, Voigt J. Scalp cooling with adjuvant/neoadjuvant chemotherapy for breast cancer and the risk of scalp metastases: systematic review and meta-analysis. Breast Cancer Res Treat. 2017;163:199-205.
31. Haksöyler V, Koseci T, Olgun P, Bayram E, Çaparlar MA. Effectiveness and Reliability of Scalp Cooling in Preventing Hair Loss Caused by Chemotherapy. Kocaeli Med J. 2021;10(Supp: 2):133-40.
32. Belum VR, de Barros Silva G, Laloni MT, et al. Cold thermal injury from cold caps used for the prevention of chemotherapy-induced alopecia. Breast Cancer Res Treat. 2016;157(2):395-400.
33. Villarreal-Garza C, Mesa-Chavez F, Peña-Curiel O, Martinez-Cannon BA, Canavati-Marcos M, Cardona-Huerta S. Impact of chemotherapy regimen and sequence on the effectiveness of scalp cooling for alopecia prevention. Breast Cancer Res Treat. 2021;185(2):453-8.
34. Lemieux J, Provencher L, Perron L, et al. No effect of scalp cooling on survival among women with breast cancer. Breast Cancer Res Treat. 2015;149(1):263-8.
35. Dilawari A, Gallagher C, Alintah P, et al. Does scalp cooling have the same efficacy in black patients receiving chemotherapy for breast cancer? Oncologist. 2021;26(4):292-e548.
36. Komen MM, Smorenburg CH, Hurk CJ, Nortier JW. Factors influencing the effectiveness of scalp cooling in the prevention of chemotherapy‐induced alopecia. Oncologist. 2013;18(7):885-91.
37. Gregory R, Cooke T, Middleton J, Buchanan R, Williams C. Prevention of doxorubicin-induced alopedia by scalp hypothermia: relation to degree of cooling. Br Med J. 1982;284(6330):1674.
38. Komen M, Smorenburg C, Nortier J, van der Ploeg T, van den Hurk C, van der Hoeven J. Results of scalp cooling during anthracycline containing chemotherapy depend on scalp skin temperature. Breast. 2016;30:105-10.
39. Betticher DC, Delmore G, Breitenstein U, Anchisi S, Zimmerli-Schwab B, Müller A, et al. Efficacy and tolerability of two scalp cooling systems for the prevention of alopecia associated with docetaxel treatment. Support Care Cancer. 2013;21(9):2565-73.
40. Kargar M, Sarvestani RS, Khojasteh HN, Heidari MT. Efficacy of penguin cap as scalp cooling system for prevention of alopecia in patients undergoing chemotherapy. J Adv Nurs. 2011;67(11):2473-7.
41. Molina MC, Bueno CÁ, Redondo IC, Lucas-Torres MIL, López EJ, Maestro AG. Effectiveness of Scalp Cooling to Prevent Chemotherapy-Induced Alopecia in Patients Undergoing Breast Cancer Treatment: A Systematic Review and Meta-analysis. Cancer Nurs. 2023;30:105-110.
2. Choi EK, Kim IR, Chang O, et al. Impact of chemotherapy‐induced alopecia distress on body image, psychosocial well‐being, and depression in breast cancer patients. Psycho Oncol. 2014;23(10):1103-10.
3. Macquart-Moulin G, Viens P, Bouscary M, Genre D, et al. Discordance between physicians' estimations and breast cancer patients' self-assessment of side-effects of chemotherapy: an issue for quality of care. Br J Cancer. 1997;76(12):1640-5.
4. Hilton S, Hunt K, Emslie C, Salinas M, Ziebland S. Have men been overlooked? A comparison of young men and women's experiences of chemotherapy‐induced alopecia. Psycho Oncol. 2008;17(6):577-83.
5. Wang J, Lu Z, Au JL-S. Protection against chemotherapy-induced alopecia. Pharm Res. 2006;23(11):2505-14.
6. Kruse M, Abraham J. Management of chemotherapy-induced alopecia with scalp cooling. J Oncol Pract. 2018;14(3):149-54.
7. Aygin D, Aysel G. Scalp Hypothermia (Penguin Cold Caps) in Preventing Alopecia in Cancer Patients. Turk J Oncol. 2020;35(2):225–36.
8. Fairlamb D. Hair changes following cytotoxic drug induced alopecia. Postgrad Med J. 1988;64(757):907.
9. Shah VV, Wikramanayake TC, DelCanto GM, et al. Scalp hypothermia as a preventative measure for chemotherapy‐induced alopecia: a review of controlled clinical trials. J Eur Acad dermatol Venereol. 2018;32(5):720-34.
10. Shin H, Jo SJ, Kim DH, Kwon O, Myung SK. Efficacy of interventions for prevention of chemotherapy‐induced alopecia: A systematic review and meta‐analysis. Int J Cancer. 2015;136(5):E442-E54.
11. Haque E, Alabdaljabar MS, Ruddy KJ, et al. Management of chemotherapy-induced alopecia (CIA): a comprehensive review and future directions. Crit Rev Oncol Hematol. 2020;156:103093.
12. Pires EM, Pinheiro RR, Lencastre A. Alopécia Permanente Pós-Quimioterapia com Resposta Favorável ao Minoxidil Tópico. Port J Derm & Venereol . 2017;75(3):297-9.
13. Phillips GS, Freret ME, Friedman DN, et al. Assessment and treatment outcomes of persistent radiation-induced alopecia in patients with cancer. JAMA Dermatol. 2020;156(9):963-72.
14. Freites-Martinez A, Shapiro J, van den Hurk C, et al. Persistent chemotherapy-induced alopecia, persistent radiotherapy-induced alopecia, and hair growth disorders related to endocrine therapy or cancer surgery. J Am Acad Dermatol. 2019;80(5):1199.
15. Fischer TW, Trüeb RM, Hänggi G, Innocenti M, Elsner P. Topical melatonin for treatment of androgenetic alopecia. Int J Trichology. 2012;4(4):236.
16. Bussoletti C, Tolaini MV, Celleno L. Efficacy of a cosmetic phyto-caffeine shampoo in female androgenetic alopecia. G Ital Dermatol Venereol. 2018;155(4):492-9.
17. D’Agostini F, Fiallo P, Ghio M, De Flora S. Chemoprevention of doxorubicin-induced alopecia in mice by dietary administration of L-cystine and vitamin B6. Arch Dermatol Res. 2013;305(1):25-34.
18. Sharquie KE, Al‐Obaidi HK. Onion juice (Allium cepa L.), a new topical treatment for alopecia areata. J Dermatol. 2002;29(6):343-6.
19. Dąbrowski T. Hair loss as a consequence of cancer chemotherapy–physical methods of prevention. A review of the literature. Contemp Oncol. 2011;15(2):95-101.
20. Katsimbri P, Bamias A, Pavlidis N. Prevention of chemotherapy-induced alopecia using an effective scalp cooling system. Eur J Cancer. 2000;36(6):766-71.
21. Marks DH, Okhovat J-P, Hagigeorges D, et al. The effect of scalp cooling on CIA-related quality of life in breast cancer patients: a systematic review. Breast Cancer Res Treat. 2019;175:267-76.
22. Kadakia KC, Rozell SA, Butala AA, Loprinzi CL. Supportive cryotherapy: a review from head to toe. J Pain Symptom Manage. 2014;47(6):1100-15.
23. Grevelman E, Breed W. Prevention of chemotherapy-induced hair loss by scalp cooling. Ann Oncol. 2005;16(3):352-8.
24. Dunnill CJ, Al‐Tameemi W, Collett A, Haslam IS, Georgopoulos NT. A clinical and biological guide for understanding chemotherapy‐induced alopecia and its prevention. Oncologist. 2018;23(1):84-96.
25. Rugo HS, Klein P, Melin SA, et al. Association between use of a scalp cooling device and alopecia after chemotherapy for breast cancer. JAMA. 2017;317(6):606-14.
26. Nangia J, Wang T, Osborne C, et al. Effect of a scalp cooling device on alopecia in women undergoing chemotherapy for breast cancer: the SCALP randomized clinical trial. JAMA. 2017;317(6):596-605.
27. Van den Hurk CJ, Peerbooms M, van de Poll-Franse LV, Nortier JW, Coebergh JWW, Breed WP. Scalp cooling for hair preservation and associated characteristics in 1411 chemotherapy patients-results of the Dutch Scalp Cooling Registry. Acta Oncol. 2012;51(4):497-504.
28. Forsberg S. Scalp cooling therapy and cytotoxic treatment. Lancet.2001;357(9262):1134.
29. Lemieux J, Amireault C, Provencher L, Maunsell E. Incidence of scalp metastases in breast cancer: a retrospective cohort study in women who were offered scalp cooling. Breast Cancer Res Treat. 2009;118(3):547-52.
30. Rugo HS, Melin SA, Voigt J. Scalp cooling with adjuvant/neoadjuvant chemotherapy for breast cancer and the risk of scalp metastases: systematic review and meta-analysis. Breast Cancer Res Treat. 2017;163:199-205.
31. Haksöyler V, Koseci T, Olgun P, Bayram E, Çaparlar MA. Effectiveness and Reliability of Scalp Cooling in Preventing Hair Loss Caused by Chemotherapy. Kocaeli Med J. 2021;10(Supp: 2):133-40.
32. Belum VR, de Barros Silva G, Laloni MT, et al. Cold thermal injury from cold caps used for the prevention of chemotherapy-induced alopecia. Breast Cancer Res Treat. 2016;157(2):395-400.
33. Villarreal-Garza C, Mesa-Chavez F, Peña-Curiel O, Martinez-Cannon BA, Canavati-Marcos M, Cardona-Huerta S. Impact of chemotherapy regimen and sequence on the effectiveness of scalp cooling for alopecia prevention. Breast Cancer Res Treat. 2021;185(2):453-8.
34. Lemieux J, Provencher L, Perron L, et al. No effect of scalp cooling on survival among women with breast cancer. Breast Cancer Res Treat. 2015;149(1):263-8.
35. Dilawari A, Gallagher C, Alintah P, et al. Does scalp cooling have the same efficacy in black patients receiving chemotherapy for breast cancer? Oncologist. 2021;26(4):292-e548.
36. Komen MM, Smorenburg CH, Hurk CJ, Nortier JW. Factors influencing the effectiveness of scalp cooling in the prevention of chemotherapy‐induced alopecia. Oncologist. 2013;18(7):885-91.
37. Gregory R, Cooke T, Middleton J, Buchanan R, Williams C. Prevention of doxorubicin-induced alopedia by scalp hypothermia: relation to degree of cooling. Br Med J. 1982;284(6330):1674.
38. Komen M, Smorenburg C, Nortier J, van der Ploeg T, van den Hurk C, van der Hoeven J. Results of scalp cooling during anthracycline containing chemotherapy depend on scalp skin temperature. Breast. 2016;30:105-10.
39. Betticher DC, Delmore G, Breitenstein U, Anchisi S, Zimmerli-Schwab B, Müller A, et al. Efficacy and tolerability of two scalp cooling systems for the prevention of alopecia associated with docetaxel treatment. Support Care Cancer. 2013;21(9):2565-73.
40. Kargar M, Sarvestani RS, Khojasteh HN, Heidari MT. Efficacy of penguin cap as scalp cooling system for prevention of alopecia in patients undergoing chemotherapy. J Adv Nurs. 2011;67(11):2473-7.
41. Molina MC, Bueno CÁ, Redondo IC, Lucas-Torres MIL, López EJ, Maestro AG. Effectiveness of Scalp Cooling to Prevent Chemotherapy-Induced Alopecia in Patients Undergoing Breast Cancer Treatment: A Systematic Review and Meta-analysis. Cancer Nurs. 2023;30:105-110.
| Files | ||
| Issue | Vol 15 No 2 (2023) | |
| Section | Reviews | |
| Keywords | ||
| Cancer; Chemotherapy; Alopecia; Prevention | ||
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How to Cite
1.
Eslami B, Alipour S, Hessamiazar S. Chemotherapy Induced Alopecia and Scalp cooling Methods: A review of literature. Basic Clin Cancer Res. 2024;15(2):94-102.
