Original Articles

Treatment of Severe Urinary Incontinence following Radical Prostatectomy: Experience with Bioceram as a Bulking Agent

Abstract

Background: To evaluate the efficacy of Bioceram injection in men with severe stress urinary incontinence following radical prostatectomy.Methods: A total of 18 patients underwent retrograde injection of Bioceram for severe stress urinary incontinence following radical prostatectomy. Evaluation by pad test, international consultation on the Incontinence Questionnaire - Short Form (ICIQ-SF) and American Urology Association Symptom Score - Quality of Life (AUASS-QOL) was performed before and after injection therapy. Patients were considered cured if they were using no pads or only one safety pad per day.Results: Of 18 patients, 14 had received postoperative external beam radiation therapy. Furthermore, 5 patients required transurethral incision due to simultaneous stricture of the urethrovesical anastomosis. The baseline daily pad count changed from a mean of 6.1± 0.8 to 5.3 ± 1.7 (p = 0.010). None of the patients were cured and only 3 patients showed signs of improvement following injection.Conclusion: In patients with severe urinary incontinence, treatment with bulking agent injection is associated with modest efficacy.

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IssueVol 11 No 2 (2019) QRcode
SectionOriginal Articles
DOI https://doi.org/10.18502/bccr.v11i2.1656
Keywords
Bioceram Bulking Agent Radical Prostatectomy Urinary Incontinence

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How to Cite
1.
Ayati M, Amini E, Momeni SA, Ohadian Moghadam S, Nowroozi MR, Shahrokhi Damavand R. Treatment of Severe Urinary Incontinence following Radical Prostatectomy: Experience with Bioceram as a Bulking Agent. Basic Clin Cancer Res. 2019;11(2):90-95.