Prevalence and Incidence of Premenopausal and Postmenopausal Breast Cancer in Iran in 2010
Abstract
Background: We studied the patterns of premenopausal and postmenopausal breast cancer incidence and its established risk factors in Iran in 2010. In addition, we estimated the 5-year prevalence of breast cancer in the country.Methods: We performed an internet and library literature review. We used national cancer registry data, demographic health surveys, national censuses and World Bank data in this study. We used incidence rate and weighted survival rate of breast cancer and estimated five-year prevalence of breast cancer in Iran.Results: Incidence rate of postmenopausal breast cancer varied significantly within country. The highest ASR was in Tehran province and reached 164.1 Per 100000 and the lowest ASR (13.9/100000) belonged to Sistan & Baluchistan. We found significant inverse correlation between postmenopausal breast cancer incidence and family size(r=-0.579, p=0.001), illiteracy ratio (r=-0.703, p<0.0001), and direct correlation for urbanization ratio (r=0.554, p=0.002) and life expectancy(r=0.659, p<0.0001). However one to six month breastfeeding was not significantly correlated with postmenopausal breast cancer incidence. Adjusting for the 15% underestimation in the pathology based cancer registry, the estimated number of new breast cancer was about 10,000 and the five-year prevalence was about 40, 0000. Conclusion: Postmenopausal breast cancer is increasing in Iran. We suggest planning for the primary prevention and cost-effective early detection program for breast cancer in Iran, particularly for postmenopausal breast cancer which is going to be the main burden in the near future.Ferlay J, Shin H, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer.127:2893-917.
Jemal A, Center MM, DeSantis C, Ward EM. Global patterns of cancer incidence and mortality rates and trends. Cancer Res;19:1893-907.
Bray F, McCarron P, Parkin DM. The changing global patterns of female breast cancer incidence and mortality. Childhood. 2004;4:5.
Iranian cancer registry national report: ministry of health; non-communicable disease management center; cancer office; 2009.
Buell P, Dunn JE. Cancer mortality among Japanese issei and nisei of California. Cancer. 1965;18: 656-64.
Lacey JV, Devesa SS, Brinton LA. Recent trends in breast cancer incidence and mortality. Environ Mol Mutagen. 2002;39: 82-88.
Deapen D, Liu L, Perkins C, Bernstein L, Ross RK. Rapidly rising breast cancer incidence rates among Asian American women. Int J Cancer. 2002;99: 747-50.
Moller T, Olsson Hk, Ranstam J, Bergkvist L. Breast cancer and breastfeeding: collaborative reanalysis of individual data from 47 epidemiological studies in 30 countries, including 50302 women with breast cancer and 96973 women without the disease. Lancet. 2002;360:187-95.
Naieni KH, Ardalan A, Mahmoodi M, Motevalian A, Yahyapoor Y, Yazdizadeh B. Risk factors of breast cancer in north of Iran: a case-control in Mazandaran Province. Asian Pacific Journal of Cancer Prevention. 2007;8:395.
Ghiasvand R, Bahmanyar S, Zendehdel K, et al. Postmenopausal breast cancer in Iran; risk factors and their population attributable fractions. BMC cancer; 12: 414.
Ebrahimi M, Vahdaninia M, Montazeri A. Risk factors for breast cancer in Iran: a case-control study. Breast Cancer Research. 2002;4: R10.
Montazeri A, Sadighi J, Farzadi F, et al. Weight, height, body mass index and risk of breast cancer in postmenopausal women: a case-control study. BMC cancer. 2008; 8: 278.
Yavari P, Mosavizadeh M, Sadrol-Hefazi B, Mehrabi Y. Reproductive characteristics and the risk of breast cancer--a case-control study in Iran. Asian Pacific journal of cancer prevention. 2005;6: 370.
Akbari ME, Akbari M, Zirakzadeh H, Nafisi N, Heidari A, Hosseinizadegan Shirazi F. Margin status influence on the outcome of patients treated with breast conserving surgery. Iranian Journal of Cancer Prevention; 4(4):177-82.
Mousavi SM, Mohagheghi MA, Mousavi-Jerrahi A, Nahvijou A, Seddighi Z. Outcome of breast cancer in Iran: A study of Tehran cancer registry data. Asian Pacific journal of cancer prevention. 2008;9(2):275-78.
Vahdaninia M, Harir CA, Montazeri A. Five-year survival in Iranian breast cancer patients: A prospective study. Payesh. 2003.
Abolhasani F, Khayamzadeh M, Moradi LM, Jamali A, Salmanian R, Naghavi M. Estimation of breast cancer burden in Iran in 2003 and its comparison with Eastern Mediterranean region and the World in 2002. Payesh. 2007.
Heydari ST, Mehrabani D, Tabei SZ, Azarpira N, Vakili MA. Survival of breast cancer in southern Iran. Iranian Journal of Cancer Prevention; 2: 51-4.
Akbari ME, Mirzaei HR, Soori H. year survival of breast cancer in Shohada-e-Tajrish and Jorjani hospitals. Hakim. 2006; 9: 39-44.
Akbari M, Khayamzadeh M, Khoshnevis SJ, Nafisi N, Akbari A. Five and ten years survival in breast cancer patients mastectomies vs. breast conserving surgeries personal experience. Iranian Journal of Cancer Prevention; 1: 53-6.
Mousavi SM, Mohaghegghi MA, Mousavi-Jerrahi A, Nahvijou A, Seddighi Z. Burden of breast cancer in Iran: a study of the Tehran population based cancer registry. Asian Pacific Journal of Cancer Prevention. 2006; 7:571.
Akbari ME, Mozaffar M, Heidari A, et al. Recurrence and Survival Effect in Breast Conserving Surgery: What are the Predictive and/or Prognostic Factors? Iranian Journal of Cancer Prevention; 4(2):49-54.
Akbari M, Movahedi M, Haghighat S, Khayamzadeh M, Moradi A, Mirzaei H. Survival Rate of Breast Cancer Based on Geographical Region in Iran: A National Study. Ann Oncol. 2011;22:64
Pisani P, Bray F, Parkin DM. Estimates of the worldwide prevalence of cancer for 25 sites in the adult population. Int J Cancer. 2002;97: 72-81.
zendehdel k, sedighi z, hassanloo j, nahviju a. Improving Quality of Cancer Registration in Iran. Part1: Evaluation and Comparison of Cancer Registration Results in the Country. Hakim. 2010;12:42-9.
Gomez SL, Noone A-M, Lichtensztajn DY, et al. Cancer Incidence Trends Among Asian American Populations in the United States, 1990-2008. J Natl Cancer Inst; 105:1096-110.
Annual statistics for tuberculosis, 2006, Iranian ministry of health, center for disease control.
Hortobagyi GN, de la Garza Salazar J, Pritchard K, et al. The global breast cancer burden: variations in epidemiology and survival. Clinical breast cancer.2005;6: 391-401.
Malik K. human development index report 2013; 2013.
Bray F, Jemal A, Grey N, Ferlay J, Forman D. Global cancer transitions according to the Human Development Index (2008-2030): a population-based study. The Lancet Oncology;13(8):790-801.
Boyle P, Howell A. The globalisation of breast cancer. Breast Cancer Research;12(Suppl 4):S7.
Althuis MD, Fergenbaum JH, Garcia-Closas M, Brinton LA, Madigan MP, Sherman ME. Etiology of hormone receptor defined breast cancer: a systematic review of the literature. Cancer Res. 2004;13:1558-68.
Hemminki K, Forsti A, Sundquist J, Mousavi SM. Preventable breast cancer is postmenopausal. Breast Cancer Res Treat;125:163-7.
Ghiasvand R, Maram ES, Tahmasebi S, Tabatabaee SHR. Risk factors for breast cancer among young women in southern Iran. Int J Cancer;129:1443-9.
Gajalakshmi V, Mathew A, Brennan P, et al. Breastfeeding and breast cancer risk in India: A multicenter case control study. Int J Cancer. 2009;125: 662-5.
Lipworth L, Bailey LR, Trichopoulos D. History of breast-feeding in relation to breast cancer risk: a review of the epidemiologic literature. J Natl Cancer Inst. 2000;92:302-12.
| Files | ||
| Issue | Vol 5 No 3 (2013) | |
| Section | Original Articles | |
| Keywords | ||
| Breast cancer Incidence Prevalence Epidemiology Iran | ||
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