The diagnostic performance of magnetic resonance imaging (MRI) in the evaluation of breast ultrasound non-mass lesions: a systematic review
Evaluation of breast non-mass lesions
-
Nasrin Ahmadinejad
,
Mohammad Hossein Golezar
,
Maedeh Rouzbahani
,
Sara Hassanzadeh
,
Mohsen Rastkar
Abstract
Aim: The purpose of this study is to conduct a systematic review of the current knowledge regarding the diagnostic performance of MRI in the investigation of non-mass lesions of the breast.Method: Up to July 2022, PubMed, Scopus, Web of Science, and Embase were searched comprehensively. All studies examining the diagnostic performance of MRI in non-mass lesions were included except review articles, articles published in a language other than English, and case reports or series of cases. A literature review and data extraction were performed by two independent reviewers. A checklist for cross-sectional studies developed by the Joanna Briggs Institute (JBI) was used to assess sources of bias. Results: The systematic review included two studies. If any enhancement is present on MRI, most ultrasound NMLs will exhibit a non-mass-enhancement. We found that the distribution of non-mass enhancement lesions was primarily segmental and regional. The highest number of malignancies is associated with segmental distributions, since 81.8% of the cases with segmental enhancement were ductal carcinomas, specifically DCIS.Conclusion: Non-mass lesions of the US that do not enhance in MRI have a good prognosis. Breast cancer is very unlikely in these cases, so follow-up is acceptable unless there is a suspicion of malignancy on mammography. In cases where regional and segmental enhancement of NMLs occurs on CE-MRI, ductal carcinomas may be present, and a pathological examination is warranted.
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2. Are C, Rajaram S, Are M, Raj H, Anderson BO, Chaluvarya Swamy R, et al. A review of global cancer burden: trends, challenges, strategies, and a role for surgeons. J Surg Oncol. 2013 Feb;107(2):221–6.
3. Hooley RJ, Scoutt LM, Philpotts LE. Breast ultrasonography: state of the art. Radiology. 2013 Sep;268(3):642–59.
4. Kim HR, Jung HK. Histopathology findings of non-mass cancers on breast ultrasound. Acta Radiol Open. 2018 Jun;7(6):2058460118774957.
5. Kim SJ, Park YM, Jung HK. Nonmasslike lesions on breast sonography: comparison between benign and malignant lesions. J Ultrasound Med Off J Am Inst Ultrasound Med. 2014 Mar;33(3):421–30.
6. Sotome K, Yamamoto Y, Hirano A, Takahara T, Hasegawa S, Nakamaru M, et al. The role of contrast enhanced MRI in the diagnosis of non-mass image-forming lesions on breast ultrasonography. Breast Cancer Tokyo Jpn. 2007;14(4):371–80.
7. Pinker K, Helbich TH, Morris EA. The potential of multiparametric MRI of the breast. Br J Radiol. 2017 Jan;90(1069):20160715.
8. Uematsu T. Non-mass-like lesions on breast ultrasonography: a systematic review. Breast Cancer Tokyo Jpn. 2012 Oct;19(4):295–301.
9. D N, K N, Jh C, Cc H, Hj Y, O N, et al. Selection of diagnostic features on breast MRI to differentiate between malignant and benign lesions using computer-aided diagnosis: differences in lesions presenting as mass and non-mass-like enhancement. Eur Radiol [Internet]. 2010 Apr [cited 2022 Oct 28];20(4). Available from: https://pubmed.ncbi.nlm.nih.gov/19789878/
10. Breast Imaging Reporting & Data System | American College of Radiology [Internet]. [cited 2022 Oct 28]. Available from: https://www.acr.org/Clinical-Resources/Reporting-and-Data-Systems/Bi-Rads
11. Morakkabati-Spitz N, Leutner C, Schild H, Traeber F, Kuhl C. Diagnostic usefulness of segmental and linear enhancement in dynamic breast MRI. Eur Radiol. 2005 Sep;15(9):2010–7.
12. Aydin H. The MRI characteristics of non-mass enhancement lesions of the breast: associations with malignancy. Br J Radiol [Internet]. 2019 Apr [cited 2022 Oct 28];92(1096). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540851/
13. Tozaki M, Fukuda K. High-spatial-resolution MRI of non-masslike breast lesions: interpretation model based on BI-RADS MRI descriptors. AJR Am J Roentgenol. 2006 Aug;187(2):330–7.
14. Mann RM, Hoogeveen YL, Blickman JG, Boetes C. MRI compared to conventional diagnostic work-up in the detection and evaluation of invasive lobular carcinoma of the breast: a review of existing literature. Breast Cancer Res Treat. 2008 Jan;107(1):1–14.
15. Chen JH, Liu H, Baek HM, Nalcioglu O, Su MY. Magnetic resonance imaging features of fibrocystic change of the breast. Magn Reson Imaging. 2008 Nov;26(9):1207–14.
| Files | ||
| Issue | Vol 15 No 1 (2023) | |
| Section | Reviews | |
| Keywords | ||
| Non-mass lesion (NML), Breast cancer, Magnetic resonance imaging (MRI), Ultrasound (US) | ||
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Ahmadinejad N, Golezar MH, Rouzbahani M, Hassanzadeh S, Rastkar M. The diagnostic performance of magnetic resonance imaging (MRI) in the evaluation of breast ultrasound non-mass lesions: a systematic review. Basic Clin Cancer Res. 2024;15(1):1-8.
