Cancer research priorities for early diagnosis in Iran: Analyses based on Multiple-Attribute Decision Making Model
Abstract
IntroductionNational cmprehensive cancer control programs combat cancer through different measures, including primary prevention, early detection, treatment, and palliative and supportive care. Among the others, early detection programs seem to be a promising intervention and lead to lower cancer mortality. We define research priorities for the early detection of cancers in Iran.MethodsWe applied the multiple criteria decision-making (MCDM) tools using three key attributes, including "5-year prevalence", "mortality to incidence ration as severity of disease," and "economic burden," to ranked different cancers for research priorities. The priorities were ranked based on four scenarios based on the weighting of the attributes. We also used the differences in the 5-year survival between localized and advanced tumors as the effect of early detection and incorporated it as the decision rule into the priority-setting model.ResultsGastric cancer and cancers of the brain and nervous system ranked first in all the proposed scenarios. The most and least 5-year survival differences between localized and advanced cancers were observed for the kidney (80.5%) and the brain (3.3%) cancers. The top 10 priorities for early cancer detection in Iran were gastric, prostate, breast, lung, colorectal, ovarian, kidney, bladder, and cervical cancers.ConclusionWe used a quantitative method and demonstrated the priority areas for research in the early detection of cancer in Iran. Researchers and government may use these results to optimize their research strategies for cancer prevention in Iran.
1. World Health Assembly, 70. Cancer prevention and control in the context of an integrated approach. World Health Organization.2017. Available in: https://apps.who.int/iris/handle/10665/275676.
2. World Health Organization. WHO report on cancer: setting priorities, investing wisely and providing care for all. World Health Organization.2020. Available in: https://apps.who.int/iris/handle/10665/330745. License: CC BY-NC-SA 3.0 IGO.
3. Mousavi A, Riahi A, Zare A. Scientific Output and Production of Islamic Republic of Iran Researchers in the field of Cancer and Compare with Regional and World Countries (2006-2015). Research in Medicine. 2017; 41 (4):282-293.
4. Fleurence RL TD. Setting priorities for research. Health Policy.2004; 69(1):1-10.
5. Jaffee E. M., Van Dang C., Agus D. B., et al. Future cancer research priorities in the USA: A Lancet Oncology Commission. The Lancet Oncology.2017; 18(11): e653-e706.
6. Cadorin L., Bressa, V., Truccolo I, et al. Priorities for cancer research from the viewpoints of cancer nurses and cancer patients: a mixed-method systematic review. Cancer Nursing. 2020;43(3): 238-256.
7. Badrick E, Cresswell K, Ellis P, et al. Top ten research priorities for detecting cancer early. The Lancet Public Health.2019;4(11): e551.
8. Nygaard, A., Halvorsrud, L., Linnerud, S., Grov, E. K., & Bergland, A. (2019). The James Lind Alliance process approach: scoping review. BMJ open, 9(8), e027473.
9. Anonymous. 2022. Available in: http://www.cohred.org/wp-content/uploads/2012/05/Priority-Setting-brochure2.pdf.
10. Tyndale‐Biscoe S, Malcolm E, Gnanapragasam VJ. Setting priorities for prostate cancer research. Trends in Urology & Men's Health. 2012 Jan 1;3(1):31-3.
11. Peters CE, Palmer AL, Telfer J, Calvin BG, Hall AL, Davies HW, Pahwa M, Demers PA. Priority Setting for Occupational Cancer Prevention. Safety and Health at Work. 2017 Jul 20.
12. Kumar A, Sah B, Singh AR, et al. A review of multi criteria decision making (MCDM) towards sustainable renewable energy development. Renewable and Sustainable Energy Reviews. 2017; 69:596-609.
13. Guindo LA, Wagner M, Baltussen R, Rindress D, van Til J, Kind P, Goetghebeur MM. From efficacy to equity: Literature review of decision criteria for resource allocation and healthcare decision making. Cost Eff Resour Alloc. 2012;10(9):10–1186.
14. Mobinizadeh M, Raeissi P, Nasiripour AA, Olyaeemanesh A, Tabibi SJ. The health systems' priority setting criteria for selecting health technologies: A systematic review of the current evidence. Med J Islam Repub Iran. 2016 Feb 16; 30:329.
15. Sayadi M. K., Heydari M., Shahanaghi, K. Extension of VIKOR method for decision making problem with interval numbers. Applied Mathematical Modelling.2009; 33(5): 2257-2262.
16. Anonymous. 2022. Available in: https: //gco.iarc.fr/today/home.
17. Rezapour A, Nargesi S, Mezginejad F, Kemmak AR, Bagherzadeh R. The economic burden of cancer in Iran during 1995–2019: a systematic review. Iranian Journal of Public Health. 2021 Jan;50(1):35.
18. Daroudi R, Sari AA, Nahvijou A, Kalaghchi B, Najafi M, Zendehdel K. The economic burden of breast cancer in Iran. Iranian journal of public health. 2015 Sep;44(9):1225.
19. Vahdatimanesh Z, Zendehdel K, kbari Sari AA, Farhan F, Nahvijou A, Delavari A, Daroudi R. Economic burden of colorectal cancer in Iran in 2012. Medical journal of the Islamic Republic of Iran. 2017; 31:115.
20. Rezaei S, Sari AA, Woldemichael A, Soofi M, Kazemi A, Matin BK. Estimating the economic burden of lung cancer in Iran. Asian Pacific journal of cancer prevention: APJCP. 2016;17(10):4729.
21. Lee KS, Chang HS, Lee SM, Park EC. Economic burden of cancer in Korea during 2000-2010. Cancer research and treatment: official journal of Korean Cancer Association. 2015 Jul;47(3):387.
22. Baltussen R, Marsh K, Thokala P, et al. Multicriteria decision analysis to support health technology assessment agencies: benefits, limitations, and the way forward. Value in Health. 2019; 22(11): 1283-1288.
23. Oliveira M, Fontes D, Pereira T. Multicriteria Decision Making: A Case Study in the Automobile Industry. FEP, 2013.
24. Adunlin G, Diaby V, Montero AJ, et al. Multicriteria decision analysis in oncology. Health Expectations. 2015; 18(6):1812-26.
25. Zendehdel K. Cancer Statistics in I.R. Iran in 2020. Basic Clin Cancer Res. 2021;12(4):159-165.
26. Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries Lancet 2018 Mar 17; 391(10125):1023-1075.
27. Hamashima C.Systematic Review Group and Guideline Development Group for Gastric Cancer Screening Guidelines. Update version of the Japanese guidelines for gastric cancer screening. Japanese journal of clinical oncology. 2018 Jul;48(7):673-83.
28. Sugano K. Screening of gastric cancer in Asia. Best practice & research Clinical gastroenterology. 2015 Dec 1;29(6):895-905.
29. Guideline Committee of the Korean Gastric Cancer Association (KGCA), Development Working Group & Review Panel. Korean practice guideline for gastric cancer 2018: an evidence-based, multi-disciplinary approach. Journal of gastric cancer. 2019 Mar;19(1):1-48.
30. Zhang X, Li M, Chen S, Hu J, Guo Q, Liu R, Zheng H, Jin Z, Yuan Y, Xi Y, Hua B. Endoscopic screening in Asian countries is associated with reduced gastric cancer mortality: a meta-analysis and systematic review. Gastroenterology. 2018 Aug 1;155(2):347-54.
31. Hamashima C. Benefits and harms of endoscopic screening for gastric cancer. World journal of gastroenterology.2016; 22(28):6385
32. Barfar E, Rashidian, A, Hosseini H, et al. Cost-effectiveness of mammography screening for breast cancer in a low socioeconomic group of Iranian women. 2014.
33. Javadinasab H, Daroudi R, Salimzadeh H, Delavari A, Vezvaie P, Malekzadeh R. Cost-effectiveness of screening colonoscopy in an Iranian high risk population. Arch Iran Med. 2017;564 – 571.
34. Majid A, Ghiasvand R, Hadji M., et al. Priority setting for improvement of cervical cancer prevention in Iran. International journal of health policy and management.2016; 5(4), 225.
35. Fenton JJ, Weyrich MS, Durbin S, Liu Y, Bang H, Melnikow J. Prostate-Specific Antigen-Based Screening for Prostate Cancer: Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA. 2018 May 8;319(18):1914-1931. doi: 10.1001/jama.2018.3712. PMID: 29801018.
36. "Commission activities in the area of Cancer", Date access: 5/22/2018, Available in: https://ec.europa.eu/research/health/index.cfm?pg=area&areaname=cancer
37. "The EU: what's best for UK cancer research and patients", date access:5/2/2018, available in: http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(16)30063-8/fulltext
38. Farhood B, Geraily G, Alizadeh,A. Incidence and mortality of various cancers in Iran and compare to other countries: a review article. Iranian journal of public health.2018; 47(3): 309.
39. Anonymous. 2022. Available in: https://www.cancer.org/cancer/stomach-cancer/about/key-statistics.html
2. World Health Organization. WHO report on cancer: setting priorities, investing wisely and providing care for all. World Health Organization.2020. Available in: https://apps.who.int/iris/handle/10665/330745. License: CC BY-NC-SA 3.0 IGO.
3. Mousavi A, Riahi A, Zare A. Scientific Output and Production of Islamic Republic of Iran Researchers in the field of Cancer and Compare with Regional and World Countries (2006-2015). Research in Medicine. 2017; 41 (4):282-293.
4. Fleurence RL TD. Setting priorities for research. Health Policy.2004; 69(1):1-10.
5. Jaffee E. M., Van Dang C., Agus D. B., et al. Future cancer research priorities in the USA: A Lancet Oncology Commission. The Lancet Oncology.2017; 18(11): e653-e706.
6. Cadorin L., Bressa, V., Truccolo I, et al. Priorities for cancer research from the viewpoints of cancer nurses and cancer patients: a mixed-method systematic review. Cancer Nursing. 2020;43(3): 238-256.
7. Badrick E, Cresswell K, Ellis P, et al. Top ten research priorities for detecting cancer early. The Lancet Public Health.2019;4(11): e551.
8. Nygaard, A., Halvorsrud, L., Linnerud, S., Grov, E. K., & Bergland, A. (2019). The James Lind Alliance process approach: scoping review. BMJ open, 9(8), e027473.
9. Anonymous. 2022. Available in: http://www.cohred.org/wp-content/uploads/2012/05/Priority-Setting-brochure2.pdf.
10. Tyndale‐Biscoe S, Malcolm E, Gnanapragasam VJ. Setting priorities for prostate cancer research. Trends in Urology & Men's Health. 2012 Jan 1;3(1):31-3.
11. Peters CE, Palmer AL, Telfer J, Calvin BG, Hall AL, Davies HW, Pahwa M, Demers PA. Priority Setting for Occupational Cancer Prevention. Safety and Health at Work. 2017 Jul 20.
12. Kumar A, Sah B, Singh AR, et al. A review of multi criteria decision making (MCDM) towards sustainable renewable energy development. Renewable and Sustainable Energy Reviews. 2017; 69:596-609.
13. Guindo LA, Wagner M, Baltussen R, Rindress D, van Til J, Kind P, Goetghebeur MM. From efficacy to equity: Literature review of decision criteria for resource allocation and healthcare decision making. Cost Eff Resour Alloc. 2012;10(9):10–1186.
14. Mobinizadeh M, Raeissi P, Nasiripour AA, Olyaeemanesh A, Tabibi SJ. The health systems' priority setting criteria for selecting health technologies: A systematic review of the current evidence. Med J Islam Repub Iran. 2016 Feb 16; 30:329.
15. Sayadi M. K., Heydari M., Shahanaghi, K. Extension of VIKOR method for decision making problem with interval numbers. Applied Mathematical Modelling.2009; 33(5): 2257-2262.
16. Anonymous. 2022. Available in: https: //gco.iarc.fr/today/home.
17. Rezapour A, Nargesi S, Mezginejad F, Kemmak AR, Bagherzadeh R. The economic burden of cancer in Iran during 1995–2019: a systematic review. Iranian Journal of Public Health. 2021 Jan;50(1):35.
18. Daroudi R, Sari AA, Nahvijou A, Kalaghchi B, Najafi M, Zendehdel K. The economic burden of breast cancer in Iran. Iranian journal of public health. 2015 Sep;44(9):1225.
19. Vahdatimanesh Z, Zendehdel K, kbari Sari AA, Farhan F, Nahvijou A, Delavari A, Daroudi R. Economic burden of colorectal cancer in Iran in 2012. Medical journal of the Islamic Republic of Iran. 2017; 31:115.
20. Rezaei S, Sari AA, Woldemichael A, Soofi M, Kazemi A, Matin BK. Estimating the economic burden of lung cancer in Iran. Asian Pacific journal of cancer prevention: APJCP. 2016;17(10):4729.
21. Lee KS, Chang HS, Lee SM, Park EC. Economic burden of cancer in Korea during 2000-2010. Cancer research and treatment: official journal of Korean Cancer Association. 2015 Jul;47(3):387.
22. Baltussen R, Marsh K, Thokala P, et al. Multicriteria decision analysis to support health technology assessment agencies: benefits, limitations, and the way forward. Value in Health. 2019; 22(11): 1283-1288.
23. Oliveira M, Fontes D, Pereira T. Multicriteria Decision Making: A Case Study in the Automobile Industry. FEP, 2013.
24. Adunlin G, Diaby V, Montero AJ, et al. Multicriteria decision analysis in oncology. Health Expectations. 2015; 18(6):1812-26.
25. Zendehdel K. Cancer Statistics in I.R. Iran in 2020. Basic Clin Cancer Res. 2021;12(4):159-165.
26. Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries Lancet 2018 Mar 17; 391(10125):1023-1075.
27. Hamashima C.Systematic Review Group and Guideline Development Group for Gastric Cancer Screening Guidelines. Update version of the Japanese guidelines for gastric cancer screening. Japanese journal of clinical oncology. 2018 Jul;48(7):673-83.
28. Sugano K. Screening of gastric cancer in Asia. Best practice & research Clinical gastroenterology. 2015 Dec 1;29(6):895-905.
29. Guideline Committee of the Korean Gastric Cancer Association (KGCA), Development Working Group & Review Panel. Korean practice guideline for gastric cancer 2018: an evidence-based, multi-disciplinary approach. Journal of gastric cancer. 2019 Mar;19(1):1-48.
30. Zhang X, Li M, Chen S, Hu J, Guo Q, Liu R, Zheng H, Jin Z, Yuan Y, Xi Y, Hua B. Endoscopic screening in Asian countries is associated with reduced gastric cancer mortality: a meta-analysis and systematic review. Gastroenterology. 2018 Aug 1;155(2):347-54.
31. Hamashima C. Benefits and harms of endoscopic screening for gastric cancer. World journal of gastroenterology.2016; 22(28):6385
32. Barfar E, Rashidian, A, Hosseini H, et al. Cost-effectiveness of mammography screening for breast cancer in a low socioeconomic group of Iranian women. 2014.
33. Javadinasab H, Daroudi R, Salimzadeh H, Delavari A, Vezvaie P, Malekzadeh R. Cost-effectiveness of screening colonoscopy in an Iranian high risk population. Arch Iran Med. 2017;564 – 571.
34. Majid A, Ghiasvand R, Hadji M., et al. Priority setting for improvement of cervical cancer prevention in Iran. International journal of health policy and management.2016; 5(4), 225.
35. Fenton JJ, Weyrich MS, Durbin S, Liu Y, Bang H, Melnikow J. Prostate-Specific Antigen-Based Screening for Prostate Cancer: Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA. 2018 May 8;319(18):1914-1931. doi: 10.1001/jama.2018.3712. PMID: 29801018.
36. "Commission activities in the area of Cancer", Date access: 5/22/2018, Available in: https://ec.europa.eu/research/health/index.cfm?pg=area&areaname=cancer
37. "The EU: what's best for UK cancer research and patients", date access:5/2/2018, available in: http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(16)30063-8/fulltext
38. Farhood B, Geraily G, Alizadeh,A. Incidence and mortality of various cancers in Iran and compare to other countries: a review article. Iranian journal of public health.2018; 47(3): 309.
39. Anonymous. 2022. Available in: https://www.cancer.org/cancer/stomach-cancer/about/key-statistics.html
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| Issue | Vol 15 No 1 (2023) | |
| Section | Original Articles | |
| Keywords | ||
| cancer research early diagnosis | ||
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How to Cite
1.
Mobinizadeh M, Daroudi R, Mohammadi S, Nahvijou A, Zendehdel K. Cancer research priorities for early diagnosis in Iran: Analyses based on Multiple-Attribute Decision Making Model. Basic Clin Cancer Res. 2024;15(1):51-62.
