Case Reports

Subependymal giant cell astrocytoma, report of a rare case


Tuberous sclerosis complex (TSC) is a rare genetic disease that is inherited autosomal dominantly and may be associated with subependymal giant cell astrocytoma (SEGA) in 10-20% of cases. Different phenotypes are related to the form of lesions in different parts of the body, including skin, brain, kidneys, lungs, and heart. Age of patient, location of the tumor, and associated skin or neurological lesions may guide the pathologist for a definite diagnosis. Here we report a case of SEGA in an adolescent with TSC. Neurological clues including seizure and mental retardation, facial angiofibroma, renal mass, and histopathology examination of brain tumor culminated in the diagnosis of TSC and SEGA.
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IssueVol 14 No 1 (2022) QRcode
SectionCase Reports
Subependymal giant cell astrocytoma, Tuberous sclerosis complex

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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
Darvishi B, Farhad N, Ramezani M. Subependymal giant cell astrocytoma, report of a rare case. Basic Clin Cancer Res. 2023;14(1):23-27.