Subependymal giant cell astrocytoma, report of a rare case
Abstract
Tuberous sclerosis complex (TSC) is a rare genetic disease that is inherited autosomal dominantly and may be associated with subependymal giant cell astrocytoma (SEGA) in 10-20% of cases. Different phenotypes are related to the form of lesions in different parts of the body, including skin, brain, kidneys, lungs, and heart. Age of patient, location of the tumor, and associated skin or neurological lesions may guide the pathologist for a definite diagnosis. Here we report a case of SEGA in an adolescent with TSC. Neurological clues including seizure and mental retardation, facial angiofibroma, renal mass, and histopathology examination of brain tumor culminated in the diagnosis of TSC and SEGA.
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2. Tompe AP, Sargar KM, Kazmi SAJ, Shimony N. A solitary extraventricular subependymal giant cell astrocytoma in the absence of tuberous sclerosis. Radiology Case Reports. 2021;16(1):180-4.
3. Rambabova Bushljetik I, Lazareska M, Barbov I, Stankov O, Filipce V, Spasovski G. Bilateral Renal Angiomyolipomas and Subependymal Giant Cell Astrocytoma Associated with Tuberous Sclerosis Complex: a Case Report and Review of The Literature. Balkan J Med Genet. 2020;23(2):93-8.
4. Tahiri Elousrouti L, Lamchahab M, Bougtoub N, Elfatemi H, Chbani L, Harmouch T, et al. Subependymal giant cell astrocytoma (SEGA): a case report and review of the literature. J Med Case Rep. 2016;10:35.
5. Karagianni A, Karydakis P, Giakoumettis D, Nikas I, Sfakianos G, Themistocleous M. Fetal subependymal giant cell astrocytoma: A case report and review of the literature. Surg Neurol Int. 2020;11:26.
6. Kim J-Y, Jung T-Y, Lee K-H, Kim S-K. Subependymal Giant Cell Astrocytoma Presenting with Tumoral Bleeding: A Case Report. Brain Tumor Res Treat. 2017;5(1):37-41.
7. Almubarak AO, Abdullah J, Al Hindi H, AlShail E. Infantile atypical subependymal giant cell astrocytoma. Neurosciences (Riyadh). 2020;25(1):61-4.
8. Sadeghipour A, Abdi N, Babaheidarian P. CD99: A potential Diagnostic Marker for Differentiating Sub-ependymal Giant Cell Astrocytoma From Other Mimickers: A Report of Five Cases. Iran J Pathol. 2017;12(3):286-90.
9. Azarpira N, Pakbaz S, Rakei M. Subependymal giant cell astrocytoma: Cytological findings. J Cytol. 2012;29(4):276-7.
2. Tompe AP, Sargar KM, Kazmi SAJ, Shimony N. A solitary extraventricular subependymal giant cell astrocytoma in the absence of tuberous sclerosis. Radiology Case Reports. 2021;16(1):180-4.
3. Rambabova Bushljetik I, Lazareska M, Barbov I, Stankov O, Filipce V, Spasovski G. Bilateral Renal Angiomyolipomas and Subependymal Giant Cell Astrocytoma Associated with Tuberous Sclerosis Complex: a Case Report and Review of The Literature. Balkan J Med Genet. 2020;23(2):93-8.
4. Tahiri Elousrouti L, Lamchahab M, Bougtoub N, Elfatemi H, Chbani L, Harmouch T, et al. Subependymal giant cell astrocytoma (SEGA): a case report and review of the literature. J Med Case Rep. 2016;10:35.
5. Karagianni A, Karydakis P, Giakoumettis D, Nikas I, Sfakianos G, Themistocleous M. Fetal subependymal giant cell astrocytoma: A case report and review of the literature. Surg Neurol Int. 2020;11:26.
6. Kim J-Y, Jung T-Y, Lee K-H, Kim S-K. Subependymal Giant Cell Astrocytoma Presenting with Tumoral Bleeding: A Case Report. Brain Tumor Res Treat. 2017;5(1):37-41.
7. Almubarak AO, Abdullah J, Al Hindi H, AlShail E. Infantile atypical subependymal giant cell astrocytoma. Neurosciences (Riyadh). 2020;25(1):61-4.
8. Sadeghipour A, Abdi N, Babaheidarian P. CD99: A potential Diagnostic Marker for Differentiating Sub-ependymal Giant Cell Astrocytoma From Other Mimickers: A Report of Five Cases. Iran J Pathol. 2017;12(3):286-90.
9. Azarpira N, Pakbaz S, Rakei M. Subependymal giant cell astrocytoma: Cytological findings. J Cytol. 2012;29(4):276-7.
| Files | ||
| Issue | Vol 14 No 1 (2022) | |
| Section | Case Reports | |
| DOI | https://doi.org/10.18502/bccr.v14i1.14385 | |
| Keywords | ||
| Subependymal giant cell astrocytoma, Tuberous sclerosis complex | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Darvishi B, Farhad N, Ramezani M. Subependymal giant cell astrocytoma, report of a rare case. Basic Clin Cancer Res. 2023;14(1):23-27.
