Cryopreservation Options to Preserve Fertility in Female Cancer Patients: Available Clinical Practice and Investigational Strategies from the Oncology Guidelines Point of View
Abstract
In recent years, advances in cancer treatment have improved the survival rate of cancer patients significantly. However, destructive damage to ovaries due to the therapies or cancer itself can cause different degrees of infertility in women of reproductive age that can affect their quality of life seriously. In this study, fertility cryopreservation options for female cancer patients in oncology guidelines were reviewed. Cryopreservation methods have a long history in reproductive biology and oncology. However, embryo and oocyte cryopreservation were the eligible restoration strategies in clinical oncology practice. Ovarian tissue cryopreservation (OTC) is the latest option recommended for fertility preservation in pre-pubertal and adult patients who cannot delay their treatment or in whom taking IVF hormones may have adverse effects on their cancer. Reports show that frozen-thawed ovarian tissue transplantation has led to more than 130 live births so far in patients, most of whom were cancer patients. Although OTC is indeed generally recognized as an investigational method, it is recommended in some important guidelines, such as ASCO 2018. Therefore, based on many clinical pieces of evidence, it is predicted that the investigational label will soon be removed, and OTC might be considered as one of the main fertility preservation options for female cancer patients in clinical oncology practice.
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2. Tiong V, Rozita A, Taib N, Yip C, Ng C. Incidence of chemotherapy-induced ovarian failure in premenopausal women undergoing chemotherapy for breast cancer. World journal of surgery. 2014;38(9):2288-96.
3. Mahnaz Haddadi et al. Systematic Review of Available Guidelines on Fertility Preservation of Young Patients with Breast Cancer. Asian Pac J Cancer Prev, 16 (3), 1057-1062.
4. Rodriguez-Wallberg KA, Oktay K. Options on fertility preservation in female cancer patients. Cancer treatment reviews. 2012;38(5):354-61.
5. Zeltzer LK. Cancer in adolescents and young adults psychosocial aspects. Long‐term survivors. Cancer. 1993;71(S10):3463-8.
6. Woodruff, Teresa K. “The Oncofertility Consortium--addressing fertility in young people with cancer.” Nature reviews. Clinical oncology vol. 7,8 (2010): 466-75. doi:10.1038/nrclinonc.2010.81
7. Forman EJ, Anders CK, Behera MA. Pilot survey of oncologists regarding treatment-related infertility and fertility preservation in female cancer patients. The Journal of reproductive medicine. 2009;54(4):203.
8. Kim S, Lee Y, Lee S, Kim T. Ovarian tissue cryopreservation and transplantation in patients with cancer. Obstetrics & gynecology science. 2018;61(4):431-42.
9. Anazodo, Antoinette et al. “How can we improve oncofertility care for patients? A systematic scoping review of current international practice and models of care.” Human reproduction update vol. 25,2 (2019): 159-179. doi:10.1093/humupd/dmy038
10. Armuand GM, Rodriguez-Wallberg KA, Wettergren L, Ahlgren J, Enblad G, Höglund M, et al. Sex differences in fertility-related information received by young adult cancer survivors. Journal of Clinical Oncology. 2012;30(17):2147-53.
11. Lee S, Ozkavukcu S, Heytens E, Moy F, Oktay K. Value of early referral to fertility preservation in young women with breast cancer. Journal of Clinical Oncology. 2010;28(31):4683.
12. Klemp JR, Kim SS, Committee IP. Fertility preservation in young women with breast cancer. Journal of assisted reproduction and genetics. 2012;29(6):469-72.
13. Loren AW, Mangu PB, Beck LN, Brennan L, Magdalinski AJ, Partridge AH, et al. Fertility preservation for patients with cancer: American Society of Clinical Oncology clinical practice guideline update. Journal of Clinical Oncology. 2013;31(19):2500.
14. Zeilmaker, G H et al. “Two pregnancies following transfer of intact frozen-thawed embryos.” Fertility and sterility vol. 42,2 (1984): 293-6. doi:10.1016/s0015-0282(16)48029-5
15. Donnez J, Dolmans M-M. Fertility preservation in women. New England Journal of Medicine. 2017;377(17):1657-65.
16. Rienzi L, Gracia C, Maggiulli R, LaBarbera AR, Kaser DJ, Ubaldi FM, et al. Oocyte, embryo and blastocyst cryopreservation in ART: systematic review and meta-analysis comparing slow-freezing versus vitrification to produce evidence for the development of global guidance. Human reproduction update. 2017;23(2):139-55.
17. Lee SJ, Schover LR, Partridge AH, Patrizio P, Wallace WH, Hagerty K, et al. American Society of Clinical Oncology recommendations on fertility preservation in cancer patients. J Clin Oncol. 2006;24(18):2917-31.
18. Lee S, Oktay K. Does higher starting dose of FSH stimulation with letrozole improve fertility preservation outcomes in women with breast cancer? Fertility and sterility. 2012;98(4):961-4. e1.
19. Wang A, Santistevan A, Cohn KH, Copperman A, Nulsen J, Miller BT, et al. Freeze-only versus fresh embryo transfer in a multicenter matched cohort study: contribution of progesterone and maternal age to success rates. Fertility and sterility. 2017;108(2):254-61. e4.
20. Gosden R. Cryopreservation: a cold look at technology for fertility preservation. Fertility and sterility. 2011;96(2):264-8.
21. "ASRM Press Release: Fertility Experts Issue New Report on Egg Freezing; ASRM Lifts "Experimental" Label from Technique". www.asrm.org. Retrieved 2017-02-01
22. Parmegiani L, Cognigni GE, Bernardi S, Ciampaglia W, Infante F, Pocognoli P, et al. Freezing within 2 h from oocyte retrieval increases the efficiency of human oocyte cryopreservation when using a slow freezing/rapid thawing protocol with high sucrose concentration. Hum reprod. 2008;23:1771–7.
23. Noyes, Nicole et al. “Oocyte cryopreservation: is it time to remove its experimental label?.” Journal of assisted reproduction and genetics vol. 27,2-3 (2010): 69-74. doi:10.1007/s10815-009-9382-y
24. Loren, Alison W et al. “Fertility preservation for patients with cancer: American Society of Clinical Oncology clinical practice guideline update.” Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 31,19 (2013): 2500-10. doi:10.1200/JCO.2013.49.2678
25. Forman EJ. Ovarian tissue cryopreservation: still experimental? Fertility and sterility. 2018;109(3):443-4.
26. Practice Committees of American Society for Reproductive Medicine, Society for Assisted Reproductive Technology. Mature oocyte cryopreservation: a guideline. Fertil Steril 2013; 99:37–43.
27. Donnez J, Dolmans MM, Demylle D, Jadoul P, Pirard C, Squifflet J, et al. Livebirth after orthotopic transplantation of cryopreserved ovarian tissue. Lancet. 2004;364(9443):1405–10
28. Oktay K, Harvey BE, Partridge AH, Quinn GP, Reinecke J, Taylor HS, et al. Fertility preservation in patients with cancer: ASCO clinical practice guideline update. J Clin Oncol. 2018;36(19):1994-2001.
29. Donnez J, Dolmans M-M, Diaz C, Pellicer A. Ovarian cortex transplantation: time to move on from experimental studies to open clinical application. Fertility and sterility. 2015;104(5):1097-8.
30. Donnez J, Jadoul P, Pirard C, Hutchings G, Demylle D, Squifflet J, et al. Live birth after transplantation of frozen-thawed ovarian tissue after bilateral oophorectomy for benign disease. Fertility and sterility. 2012;98(3):720-5.
31. Donnez J, Dolmans M-M, Squifflet J, Kerbrat G, Jadoul P. Live birth after allografting of ovarian cortex between monozygotic twins with Turner syndrome (45, XO/46, XX mosaicism) and discordant ovarian function. Fertility and sterility. 2011;96(6):1407-11.
32. Donnez J, García-Solares J, Dolmans M-M. Ovarian endometriosis and fertility preservation: a challenge in 2018. Minerva ginecologica. 2018;70(4):408-14.
33. Donnez J, Dolmans M-M. Ovarian cortex transplantation: 60 reported live births brings the success and worldwide expansion of the technique towards routine clinical practice. Journal of assisted reproduction and genetics. 2015;32(8):1167-70.
34. Donnez J, Dolmans M-M, Pellicer A, Diaz-Garcia C, Serrano MS, Schmidt KT, et al. Restoration of ovarian activity and pregnancy after transplantation of cryopreserved ovarian tissue: a review of 60 cases of reimplantation. Fertility and sterility. 2013;99(6):1503-13.
35. Stoop D, Cobo A, Silber S. Fertility preservation for age-related fertility decline. The Lancet. 2014;384(9950):1311-9.
36. Anderson RA, Cameron DA. Assessment of the effect of chemotherapy on ovarian function in women with breast cancer. Journal of clinical oncology. 2007;25(12):1630-1.
37. Seli E, Tangir J. Fertility preservation options for female patients with malignancies. Current Opinion in Obstetrics and Gynecology. 2005;17(3):299-308.
38. DEANESLY R. Immature rat ovaries grafted after freezing and thawing. Journal of Endocrinology. 1954;11(2):197-NP.
39. MUSSETT MV, PARROTT DM. Factors affecting the fertility of mice with orthotopic ovarian grafts. Reproduction. 1961;2(1):80-97.
40. Candy C, Wood M, Whittingham D. Restoration of a normal reproductive lifespan after grafting of cryopreserved mouse ovaries. Human reproduction. 2000;15(6):1300-4.
41. Gosden R, Baird D, Wade J, Webb R. Restoration of fertility to oophorectomized sheep by ovarian autografts stored at-196 C. Human Reproduction. 1994;9(4):597-603.
42. Masciangelo R, Bosisio C, Donnez J, Amorim CA, Dolmans M-M. Safety of ovarian tissue transplantation in patients with borderline ovarian tumors. Human Reproduction. 2017;33(2):212-9.
43. Meirow D, Ra'anani H, Shapira M, Brenghausen M, Chaim SD, Aviel-Ronen S, et al. Transplantations of frozen-thawed ovarian tissue demonstrate high reproductive performance and the need to revise restrictive criteria. Fertility and sterility. 2016;106(2):467-74.
44. Diaz-Garcia C, Domingo J, Garcia-Velasco JA, Herraiz S, Mirabet V, Iniesta I, et al. Oocyte vitrification versus ovarian cortex transplantation in fertility preservation for adult women undergoing gonadotoxic treatments: a prospective cohort study. Fertility and sterility. 2018;109(3):478-85. e2.
45. Oktay K, Karlikaya G. Ovarian function after transplantation of frozen, banked autologous ovarian tissue. New England Journal of Medicine. 2000;342(25):1919-.
46. Donnez J, Dolmans M-M, Demylle D, Jadoul P, Pirard C, Squifflet J, et al. Livebirth after orthotopic transplantation of cryopreserved ovarian tissue. The Lancet. 2004;364(9443):1405-10.
47. Meirow D, Levron J, Eldar-Geva T, Hardan I, Fridman E, Zalel Y, et al. Pregnancy after transplantation of cryopreserved ovarian tissue in a patient with ovarian failure after chemotherapy. New England Journal of Medicine. 2005;353(3):318-21.
48. Demeestere I, Simon P, Emiliani S, Delbaere A, Englert Y. Orthotopic and heterotopic ovarian tissue transplantation. Human reproduction update. 2009;15(6):649-65.
49. Bedaiwy MA, Falcone T. Ovarian tissue banking for cancer patients: reduction of post‐transplantation ischaemic injury: intact ovary freezing and transplantation. Human Reproduction. 2004;19(6):1242-4.
50. Martinez-Madrid B, Dolmans M-M, Van Langendonckt A, Defrère S, Donnez J. Freeze-thawing intact human ovary with its vascular pedicle with a passive cooling device. Fertility and sterility. 2004;82(5):1390-4.
51. Donnez J, Dolmans M-M. Fertility preservation in women. Nature Reviews Endocrinology. 2013;9(12):735.
52. Stern C, Gook D, Hale L, Agresta F, Oldham J, Rozen G, et al. First reported clinical pregnancy following heterotopic grafting of cryopreserved ovarian tissue in a woman after a bilateral oophorectomy. Human reproduction. 2013;28(11):2996-9.
53. Silber SJ, Lenahan KM, Levine DJ, Pineda JA, Gorman KS, Friez MJ, et al. Ovarian transplantation between monozygotic twins discordant for premature ovarian failure. New England Journal of Medicine. 2005;353(1):58-63.
54. Demeestere I, Simon P, Emiliani S, Delbaere A, Englert Y. Fertility preservation: successful transplantation of cryopreserved ovarian tissue in a young patient previously treated for Hodgkin's disease. The oncologist. 2007;12(12):1437-42.
55. Andersen CY, Rosendahl M, Byskov AG, Loft A, Ottosen C, Dueholm M, et al. Two successful pregnancies following autotransplantation of frozen/thawed ovarian tissue. Human reproduction. 2008;23(10):2266-72.
56. Dolmans MM, Manavella DD. Recent advances in fertility preservation. Journal of Obstetrics and Gynaecology Research. 2019;45(2):266-79.
57. Martin JR, Kodaman P, Oktay K, Taylor HS. Ovarian cryopreservation with transposition of a contralateral ovary: a combined approach for fertility preservation in women receiving pelvic radiation. Fertility and sterility. 2007;87(1):189. e5-. e7.
58. Kano M, Sosulski AE, Zhang L, Saatcioglu HD, Wang D, Nagykery N, et al. AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy. Proceedings of the National Academy of Sciences. 2017;114(9):E1688-E97.
59. Diedrich K, Fauser B, Devroey P. Cancer and fertility: strategies to preserve fertility. Reproductive biomedicine online. 2011;22(3):232-48.
60. Oktay, Kutluk et al. “Fertility Preservation in Patients With Cancer: ASCO Clinical Practice Guideline Update.” Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 36,19 (2018): 1994-2001. doi:10.1200/JCO.2018.78.1914
2. Tiong V, Rozita A, Taib N, Yip C, Ng C. Incidence of chemotherapy-induced ovarian failure in premenopausal women undergoing chemotherapy for breast cancer. World journal of surgery. 2014;38(9):2288-96.
3. Mahnaz Haddadi et al. Systematic Review of Available Guidelines on Fertility Preservation of Young Patients with Breast Cancer. Asian Pac J Cancer Prev, 16 (3), 1057-1062.
4. Rodriguez-Wallberg KA, Oktay K. Options on fertility preservation in female cancer patients. Cancer treatment reviews. 2012;38(5):354-61.
5. Zeltzer LK. Cancer in adolescents and young adults psychosocial aspects. Long‐term survivors. Cancer. 1993;71(S10):3463-8.
6. Woodruff, Teresa K. “The Oncofertility Consortium--addressing fertility in young people with cancer.” Nature reviews. Clinical oncology vol. 7,8 (2010): 466-75. doi:10.1038/nrclinonc.2010.81
7. Forman EJ, Anders CK, Behera MA. Pilot survey of oncologists regarding treatment-related infertility and fertility preservation in female cancer patients. The Journal of reproductive medicine. 2009;54(4):203.
8. Kim S, Lee Y, Lee S, Kim T. Ovarian tissue cryopreservation and transplantation in patients with cancer. Obstetrics & gynecology science. 2018;61(4):431-42.
9. Anazodo, Antoinette et al. “How can we improve oncofertility care for patients? A systematic scoping review of current international practice and models of care.” Human reproduction update vol. 25,2 (2019): 159-179. doi:10.1093/humupd/dmy038
10. Armuand GM, Rodriguez-Wallberg KA, Wettergren L, Ahlgren J, Enblad G, Höglund M, et al. Sex differences in fertility-related information received by young adult cancer survivors. Journal of Clinical Oncology. 2012;30(17):2147-53.
11. Lee S, Ozkavukcu S, Heytens E, Moy F, Oktay K. Value of early referral to fertility preservation in young women with breast cancer. Journal of Clinical Oncology. 2010;28(31):4683.
12. Klemp JR, Kim SS, Committee IP. Fertility preservation in young women with breast cancer. Journal of assisted reproduction and genetics. 2012;29(6):469-72.
13. Loren AW, Mangu PB, Beck LN, Brennan L, Magdalinski AJ, Partridge AH, et al. Fertility preservation for patients with cancer: American Society of Clinical Oncology clinical practice guideline update. Journal of Clinical Oncology. 2013;31(19):2500.
14. Zeilmaker, G H et al. “Two pregnancies following transfer of intact frozen-thawed embryos.” Fertility and sterility vol. 42,2 (1984): 293-6. doi:10.1016/s0015-0282(16)48029-5
15. Donnez J, Dolmans M-M. Fertility preservation in women. New England Journal of Medicine. 2017;377(17):1657-65.
16. Rienzi L, Gracia C, Maggiulli R, LaBarbera AR, Kaser DJ, Ubaldi FM, et al. Oocyte, embryo and blastocyst cryopreservation in ART: systematic review and meta-analysis comparing slow-freezing versus vitrification to produce evidence for the development of global guidance. Human reproduction update. 2017;23(2):139-55.
17. Lee SJ, Schover LR, Partridge AH, Patrizio P, Wallace WH, Hagerty K, et al. American Society of Clinical Oncology recommendations on fertility preservation in cancer patients. J Clin Oncol. 2006;24(18):2917-31.
18. Lee S, Oktay K. Does higher starting dose of FSH stimulation with letrozole improve fertility preservation outcomes in women with breast cancer? Fertility and sterility. 2012;98(4):961-4. e1.
19. Wang A, Santistevan A, Cohn KH, Copperman A, Nulsen J, Miller BT, et al. Freeze-only versus fresh embryo transfer in a multicenter matched cohort study: contribution of progesterone and maternal age to success rates. Fertility and sterility. 2017;108(2):254-61. e4.
20. Gosden R. Cryopreservation: a cold look at technology for fertility preservation. Fertility and sterility. 2011;96(2):264-8.
21. "ASRM Press Release: Fertility Experts Issue New Report on Egg Freezing; ASRM Lifts "Experimental" Label from Technique". www.asrm.org. Retrieved 2017-02-01
22. Parmegiani L, Cognigni GE, Bernardi S, Ciampaglia W, Infante F, Pocognoli P, et al. Freezing within 2 h from oocyte retrieval increases the efficiency of human oocyte cryopreservation when using a slow freezing/rapid thawing protocol with high sucrose concentration. Hum reprod. 2008;23:1771–7.
23. Noyes, Nicole et al. “Oocyte cryopreservation: is it time to remove its experimental label?.” Journal of assisted reproduction and genetics vol. 27,2-3 (2010): 69-74. doi:10.1007/s10815-009-9382-y
24. Loren, Alison W et al. “Fertility preservation for patients with cancer: American Society of Clinical Oncology clinical practice guideline update.” Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 31,19 (2013): 2500-10. doi:10.1200/JCO.2013.49.2678
25. Forman EJ. Ovarian tissue cryopreservation: still experimental? Fertility and sterility. 2018;109(3):443-4.
26. Practice Committees of American Society for Reproductive Medicine, Society for Assisted Reproductive Technology. Mature oocyte cryopreservation: a guideline. Fertil Steril 2013; 99:37–43.
27. Donnez J, Dolmans MM, Demylle D, Jadoul P, Pirard C, Squifflet J, et al. Livebirth after orthotopic transplantation of cryopreserved ovarian tissue. Lancet. 2004;364(9443):1405–10
28. Oktay K, Harvey BE, Partridge AH, Quinn GP, Reinecke J, Taylor HS, et al. Fertility preservation in patients with cancer: ASCO clinical practice guideline update. J Clin Oncol. 2018;36(19):1994-2001.
29. Donnez J, Dolmans M-M, Diaz C, Pellicer A. Ovarian cortex transplantation: time to move on from experimental studies to open clinical application. Fertility and sterility. 2015;104(5):1097-8.
30. Donnez J, Jadoul P, Pirard C, Hutchings G, Demylle D, Squifflet J, et al. Live birth after transplantation of frozen-thawed ovarian tissue after bilateral oophorectomy for benign disease. Fertility and sterility. 2012;98(3):720-5.
31. Donnez J, Dolmans M-M, Squifflet J, Kerbrat G, Jadoul P. Live birth after allografting of ovarian cortex between monozygotic twins with Turner syndrome (45, XO/46, XX mosaicism) and discordant ovarian function. Fertility and sterility. 2011;96(6):1407-11.
32. Donnez J, García-Solares J, Dolmans M-M. Ovarian endometriosis and fertility preservation: a challenge in 2018. Minerva ginecologica. 2018;70(4):408-14.
33. Donnez J, Dolmans M-M. Ovarian cortex transplantation: 60 reported live births brings the success and worldwide expansion of the technique towards routine clinical practice. Journal of assisted reproduction and genetics. 2015;32(8):1167-70.
34. Donnez J, Dolmans M-M, Pellicer A, Diaz-Garcia C, Serrano MS, Schmidt KT, et al. Restoration of ovarian activity and pregnancy after transplantation of cryopreserved ovarian tissue: a review of 60 cases of reimplantation. Fertility and sterility. 2013;99(6):1503-13.
35. Stoop D, Cobo A, Silber S. Fertility preservation for age-related fertility decline. The Lancet. 2014;384(9950):1311-9.
36. Anderson RA, Cameron DA. Assessment of the effect of chemotherapy on ovarian function in women with breast cancer. Journal of clinical oncology. 2007;25(12):1630-1.
37. Seli E, Tangir J. Fertility preservation options for female patients with malignancies. Current Opinion in Obstetrics and Gynecology. 2005;17(3):299-308.
38. DEANESLY R. Immature rat ovaries grafted after freezing and thawing. Journal of Endocrinology. 1954;11(2):197-NP.
39. MUSSETT MV, PARROTT DM. Factors affecting the fertility of mice with orthotopic ovarian grafts. Reproduction. 1961;2(1):80-97.
40. Candy C, Wood M, Whittingham D. Restoration of a normal reproductive lifespan after grafting of cryopreserved mouse ovaries. Human reproduction. 2000;15(6):1300-4.
41. Gosden R, Baird D, Wade J, Webb R. Restoration of fertility to oophorectomized sheep by ovarian autografts stored at-196 C. Human Reproduction. 1994;9(4):597-603.
42. Masciangelo R, Bosisio C, Donnez J, Amorim CA, Dolmans M-M. Safety of ovarian tissue transplantation in patients with borderline ovarian tumors. Human Reproduction. 2017;33(2):212-9.
43. Meirow D, Ra'anani H, Shapira M, Brenghausen M, Chaim SD, Aviel-Ronen S, et al. Transplantations of frozen-thawed ovarian tissue demonstrate high reproductive performance and the need to revise restrictive criteria. Fertility and sterility. 2016;106(2):467-74.
44. Diaz-Garcia C, Domingo J, Garcia-Velasco JA, Herraiz S, Mirabet V, Iniesta I, et al. Oocyte vitrification versus ovarian cortex transplantation in fertility preservation for adult women undergoing gonadotoxic treatments: a prospective cohort study. Fertility and sterility. 2018;109(3):478-85. e2.
45. Oktay K, Karlikaya G. Ovarian function after transplantation of frozen, banked autologous ovarian tissue. New England Journal of Medicine. 2000;342(25):1919-.
46. Donnez J, Dolmans M-M, Demylle D, Jadoul P, Pirard C, Squifflet J, et al. Livebirth after orthotopic transplantation of cryopreserved ovarian tissue. The Lancet. 2004;364(9443):1405-10.
47. Meirow D, Levron J, Eldar-Geva T, Hardan I, Fridman E, Zalel Y, et al. Pregnancy after transplantation of cryopreserved ovarian tissue in a patient with ovarian failure after chemotherapy. New England Journal of Medicine. 2005;353(3):318-21.
48. Demeestere I, Simon P, Emiliani S, Delbaere A, Englert Y. Orthotopic and heterotopic ovarian tissue transplantation. Human reproduction update. 2009;15(6):649-65.
49. Bedaiwy MA, Falcone T. Ovarian tissue banking for cancer patients: reduction of post‐transplantation ischaemic injury: intact ovary freezing and transplantation. Human Reproduction. 2004;19(6):1242-4.
50. Martinez-Madrid B, Dolmans M-M, Van Langendonckt A, Defrère S, Donnez J. Freeze-thawing intact human ovary with its vascular pedicle with a passive cooling device. Fertility and sterility. 2004;82(5):1390-4.
51. Donnez J, Dolmans M-M. Fertility preservation in women. Nature Reviews Endocrinology. 2013;9(12):735.
52. Stern C, Gook D, Hale L, Agresta F, Oldham J, Rozen G, et al. First reported clinical pregnancy following heterotopic grafting of cryopreserved ovarian tissue in a woman after a bilateral oophorectomy. Human reproduction. 2013;28(11):2996-9.
53. Silber SJ, Lenahan KM, Levine DJ, Pineda JA, Gorman KS, Friez MJ, et al. Ovarian transplantation between monozygotic twins discordant for premature ovarian failure. New England Journal of Medicine. 2005;353(1):58-63.
54. Demeestere I, Simon P, Emiliani S, Delbaere A, Englert Y. Fertility preservation: successful transplantation of cryopreserved ovarian tissue in a young patient previously treated for Hodgkin's disease. The oncologist. 2007;12(12):1437-42.
55. Andersen CY, Rosendahl M, Byskov AG, Loft A, Ottosen C, Dueholm M, et al. Two successful pregnancies following autotransplantation of frozen/thawed ovarian tissue. Human reproduction. 2008;23(10):2266-72.
56. Dolmans MM, Manavella DD. Recent advances in fertility preservation. Journal of Obstetrics and Gynaecology Research. 2019;45(2):266-79.
57. Martin JR, Kodaman P, Oktay K, Taylor HS. Ovarian cryopreservation with transposition of a contralateral ovary: a combined approach for fertility preservation in women receiving pelvic radiation. Fertility and sterility. 2007;87(1):189. e5-. e7.
58. Kano M, Sosulski AE, Zhang L, Saatcioglu HD, Wang D, Nagykery N, et al. AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy. Proceedings of the National Academy of Sciences. 2017;114(9):E1688-E97.
59. Diedrich K, Fauser B, Devroey P. Cancer and fertility: strategies to preserve fertility. Reproductive biomedicine online. 2011;22(3):232-48.
60. Oktay, Kutluk et al. “Fertility Preservation in Patients With Cancer: ASCO Clinical Practice Guideline Update.” Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 36,19 (2018): 1994-2001. doi:10.1200/JCO.2018.78.1914
| Files | ||
| Issue | Vol 12 No 1 (2020) | |
| Section | Reviews | |
| DOI | https://doi.org/10.18502/bccr.v12i1.5726 | |
| Keywords | ||
| Oncology guidelines cancer treatment fertility preservation cryopreservation. | ||
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How to Cite
1.
Mirzaeian L, Rafipour H, Hashemi S, Zabihzadeh S, Amanpour S. Cryopreservation Options to Preserve Fertility in Female Cancer Patients: Available Clinical Practice and Investigational Strategies from the Oncology Guidelines Point of View. Basic Clin Cancer Res. 2020;12(1):42-53.
