Epidemiological Features of Mycosis Fungoides in Isfahan, Iran: a 3-Years Study
Abstract
Background: Mycosis Fungoides (MF) is he most common and indolent form of Cutaneuse T-cell Lymphomas (CTCL), that usually occurs in old adults.Objectives: To determine epidemiologic features and patients characteristics of MF in Isfahan (Iran).Methods: We performed a retrospective study in MF clinic of alzahra hospital that is the main center for treatment of MF patients in Isfahan (Iran) and evaluated clinicopathologic features.Results: in 3 years 25 patients were referred to Alzahra MF clinic. 18 patients diagnosed as MF. Seven (38.9%) patients were male and 11 (61.1%) were female with male to female ratio of 1:1.57. The mean age of patients was 41.06 years. 88.9% of our patients were in stages ΙA and ΙB.Conclusion: most of our patients presented in early stages that were similar to other studies, while male: female ratio is different from other studies.Parker SR, Bethaney JV. Cutaneous T cell lymphoma-mycosis fun- goides and Sezary syndrome: an update. G Ital Dermatol Venereol 2009 Aug;144(4):467-85.
Weinstock MA, Gardstein B. Twenty-year trends in the reported in- cidence of mycosis fungoides and associated mortality. Am J Public Health 1999 Aug;89(8):1240-4.
Samuelson E. Cutaneous T-cell lymphomas. Semin Oncol Nurs 1998 Nov;14(4):293-301.
Worobec-Victor SM. Cutaneous T cell lymphoma. N J Med 1989 May;86(5):395-400.
Patel SP, Holtermann OA. Mycosis fungoides: an overview. J Surg Oncol 1983 Apr;22(4):221-7.
Keehn CA, Belongie IP, Shistik G, Fenske NA, Glass LF. The di- agnosis, staging, and treatment options for mycosis fungoides. Cancer Control 2007 Apr;14(2):102-11.
Pimpinelli N, Olsen EA, Santucci M, Vonderheid E, Haeffner AC, Stevens S, et al. Defining early mycosis fungoides. J Am Acad Dermatol 2005 Dec;53(6):1053-63.
Tuyp E, Burgoyne A, Aitchison T, MacKie R. A case-control study of possible causative factors in mycosis fungoides. Arch Dermatol 1987 Feb;123(2):196-200.
Morales-Suarez-Varela MM, Olsen J, Johansen P, Kaerlev L, Guenel P, Arveux P, et al. Occupational risk factors for mycosis fungoides: a European multicenter case-control study. J Occup Environ Med 2004 Mar;46(3):205-11.
Swerdlow S, Campo E, Harris N, Jaffe E, Pileri A, Stein H, et al. WHO classification of tumours of haemopoietic and lymphatic tissue. lyon: IARC Press; 2008.
Olsen E, Vonderheid E, Pimpinelli N, Willemze R, Kim Y, Knobler R, et al. Revisions to the staging and classification of mycosis fungoi- des and Sezary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC). Blood 2007;110(6):1713-22.
van Dongen JJ, Langerak AW, Bruggemann M, Evans PA, Hum- mel M, Lavender FL, et al. Design and standardization of PCR prim- ers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia 2003 Dec;17(12):2257-317.
Ishiji T, Takagi Y, Niimura M. Cutaneous lymphomas in Tokyo: analysis of 62 cases in a dermatology clinic. Int J Dermatol 2001 Jan;40(1):37-40.
Assaf C, Gellrich S, Steinhoff M, Nashan D, Weisse F, Dippel E, et al. Cutaneous lymphomas in Germany: an analysis of the Central Cu- taneous Lymphoma Registry of the German Society of Dermatology (DDG). J Dtsch Dermatol Ges 2007 Aug;5(8):662-8.
Criscione VD, Weinstock MA. Incidence of cutaneous T-cell lymphoma in the United States, 1973-2002. Arch Dermatol 2007 Jul;143(7):854-9.
Saunes M, Nilsen TI, Johannesen TB. Incidence of primary cutane- ous T-cell lymphoma in Norway. Br J Dermatol 2009 Feb;160(2):376-9.
Gurney KA, Cartwright RA. Increasing incidence and descriptive epidemiology of extranodal non-Hodgkin lymphoma in parts of Eng- land and Wales. Hematol J 2002;3(2):95-104.
Ku LS, Lo KK. Mycosis fungoides--a retrospective study of 40 cases in Hong Kong. Int J Dermatol 2005 Mar;44(3):215-20.
Manuchehri HM, Rakhshan M. Characteristics of primary cutane- ous lymphomas in Tehran, Iran (1998-2004). J Eur Acad Dermatol Ve- nereol 2006 Jul;20(6):758-60.
Khooei AR, Keramat MR. Cutaneous lymphomas and pseudolym- phomas: A ten-year study at Emam Reza and Omid hospitals in Mash- had, using immunohistochemical and new classification methods. IRA- NIAN JOURNAL OF DERMATOLOGY 2005;31(8):201-10.
Hamideh H, Hamideh A, Farideh G, Neda Y. Demographic and Clinical Features of Mycosis Fungoides in Tabriz, Iran. Iran J Med Sci 2009;34(2):152.
Salehi M, Azimi Z, Fatemi F, Rajabi P, Kazemi M, Amini G. In- cidence rate of mycosis fungoides in Isfahan (Iran). J Dermatol 2010 Aug;37(8):703-7.
Zinzani PL, Ferreri AJ, Cerroni L. Mycosis fungoides. Crit Rev On- col Hematol 2008 Feb;65(2):172-82.
Kim EJ, Lin J, Junkins-Hopkins JM, Vittorio CC, Rook AH. My- cosis fungoides and sezary syndrome: an update. Curr Oncol Rep 2006 Sep;8(5):376-86.
Tan ES, Tang MB, Tan SH. Retrospective 5-year review of 131 pa- tients with mycosis fungoides and Sezary syndrome seen at the National Skin Centre, Singapore. Australas J Dermatol 2006 Nov;47(4):248-52.
Alsaleh QA, Nanda A, Al-Ajmi H, Al-Sabah H, Elkashlan M, Al-Sh- emmari S, et al. Clinicoepidemiological features of mycosis fungoides in Kuwait, 1991-2006. Int J Dermatol 2010 Dec;49(12):1393-8.
van DR, Van Haselen CW, van V, V, Geerts ML, Heule F, de RM, et al. Mycosis fungoides: disease evolution and prognosis of 309 Dutch patients. Arch Dermatol 2000 Apr;136(4):504-10.
Files | ||
Issue | Vol 4 No 3&4 (2012) | |
Section | Original Articles | |
Keywords | ||
#No Keywords# |
Rights and permissions | |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |