Original Articles

In Vivo Dosimetry Evaluation of External Photon Treatments of Brain, Pelvis and Breast Cancer with Diode Dosimeters

Abstract

Background: Delivering the maximum dose to tumor while achieving the minimum dose delivery to normal tissue; is the most important goal in external radiotherapy. Diode in vivo dosimetry is widely considered to be an important tool for quality improvement of patient care in external radiotherapy. Uncertainty in dose delivery should fall within 5% of the prescribed dose as recommended by International Commission of Radiological Units and Measurement (ICRU).Materials and methods: In vivo dosimetry was implemented for treatments of 36 pelvis and 38 breast cancer patients which were treated by 60Co photon irradiation and 38 brain cancer patients which were treated by 6MV photon irradiation. The diode dosimeters that were used in this study were two different models of PTW products, T60010L model was used for 60Co photon beam and T60010M model was used for 6MV photon beams.Results: The frequency histograms of the relative difference between the expected and measured doses at breast, pelvis and brain treatments, have mean values and standard deviations of -1.21% ( 7.01%), -0.44% ( 4.06%) and -1.32% ( 5.08%) , respectively. Our study showed that the accurate prediction of the dose value at breast cancer treatment is harder than that at brain and pelvis cancer treatment and requires an estimation of the lack of scatter due to missing tissue.Conclusions: Quantitative verification of the prescribed daily dose is important in external radiotherapy to ensure precision in patient set-up accuracy in dose delivery.

Essers M, Mijnheer BJ. In vivo dosimetry during external photon beam radiotherapy. Int J Radiat Oncol Biol Phys. 1999 Jan 15;43(2):245-59.

Loncol T, Greffe JL, Vynckier S, Scalliet P. Entrance and exit dose measurements with semiconductors and thermoluminescent dosemeters: a comparison of methods and in vivo results. Radiother Oncol. 1996 Nov;41(2):179-87.

Millwater CJ, MacLeod AS, Thwaites DI. In vivo semiconductor dosimetry as part of routine quality assurance. Br J Radiol. 1998 Jun;71(846):661-8.

Tung CJ, Wang HC, Lo SH, Wu JM, Wang CJ. In vivo dosimetry for external photon treatments of head and neck cancers by diodes and TLDS. Radiat Prot Dosimetry. 2004;111(1):45-50.

Allahverdi M, Geraily G, Esfehani M, Sharafi A, Haddad P, Shirazi A. Dosimetry and verification of 60Co total body irradiation with human phantom and semiconductor diode. J Med phys. 2007;32:169-74.

Allahverdi M, Taghizadeh MR. Achievable accuracy in brain tumors by in vivo dosimetry with diode detectors. Iranian Journal of Radiation Research. 2006;3(4):153-61.

Broggi S, Fiorino C, Calandrino R. In vivo estimation of midline dose maps by transit dosimetry in head and neck radiotherapy. Br J Radiol. 2002 Dec;75(900):974-81.

Wolff T, Carter S, Langmack KA, Twyman NI, Dendy PP. Characterization and use of a commercial n-type diode system. Br J Radiol. 1998 Nov;71(851):1168-77.

Dam J, Marinello G. Methods for in vivo dosimetry in external radiotherapy. ESTRO booklet (Belgium:Garant). 2006;6

Huyskens D, Bogaerts R, Verstraete J, Loof M, Nystrom H, Fiorino C, et al. Practical guidelines for the implementation of in vivo dosimetry with diodes in external radiotherapy with photon beams (entrance dose). ESTRO booklet (Belgium:Garant). 2001;5.

Leunens G, Van Dam J, Dutreix A, van der Schueren E. Quality assurance in radiotherapy by in vivo dosimetry. 2. Determination of the target absorbed dose. Radiother Oncol. 1990 Sep;19(1):73-87.

Rizzotti A, Compri C, Garusi GF. Dose evaluation to patients irradiated by 60Co beams, by means of direct measurement on the incident and on the exit surfaces. Radiother Oncol. 1985 Apr;3(3):279-83.

Allahverdi M, Geraily G, Esfehani M, Sharafi A, Shirazi A. Diode calibration for dose determination in total body irradiation Iran J Radiat Res. 2008;6(1):43-50.

Fiorino C, Corletto D, Mangili P, Broggi S, Bonini A, Cattaneo GM, et al. Quality assurance by systematic in vivo dosimetry: results on a large cohort of patients. Radiother Oncol. 2000 Jul;56(1):85-95.

Heukelom S, Lanson JH, van Tienhoven G, Mijnheer BJ. In vivodosimetry during tangential breast treatment. Radiother Oncol. 1991 Dec;22(4):269-79.

Rodriguez ML, Abrego E, Pineda A. Implementation of in vivo dosimetry with Isorad semiconductor diodes in radiotherapy treatments of the pelvis. Med Dosim. 2008 Spring;33(1):14-21.

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IssueVol 3 No 2 (2011) QRcode
SectionOriginal Articles
Keywords
External radiotherapy in vivo dosimetry Diode dosimeter

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How to Cite
1.
Mohammadkarim A, Allahverdi M, Esfehani M, Nedaie H, Shirazi A. In Vivo Dosimetry Evaluation of External Photon Treatments of Brain, Pelvis and Breast Cancer with Diode Dosimeters. Basic Clin Cancer Res. 2016;3(2):26-30.