Basic & Clinical Cancer Research 2017. 9(3):46-49.

Microinvasive Papillary carcinoma of the breast with mucinous differentiation and high grade ductal carcinoma in situ: A case report study
Mazaher Ramezani, Farhad Amirian, Kowsar Badfar, Kaivan Mohammadi, Farhad Kavousi, Masoud Sadeghi


Invasive papillary carcinoma of the breast is a rare form of breast cancer with the prevalence of about 0.5 to 2% of all diagnosed invasive breast tumors. This study aimed to report the first case of microinvasive papillary carcinoma with mucinous differentiation and ductal carcinoma in situ component. A 35-year-old woman had a history of left breast mass without pain, discharge or weight loss. Fine needle aspiration noticed papillary carcinoma. Frozen section diagnosis was invasive carcinoma with papillary feature and free marked margin. Permanent diagnosis on May 4,2017 showed microinvasive papillary carcinoma with ductal carcinoma in situ, high grade and mucinous carcinoma. The tumor didn't have frank invasion and metastasis. In conclusion, microinvasive papillary carcinoma is a tumor with minimal invasion and low axillary lymph node metastasis that can combine to mucinous differentiation and/or ductal carcinoma in situ component.


Papillary carcinoma; Breast; Mucin; Ductal carcinoma in situ; Case report

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