Tehran University of Medical Sciences Basic & Clinical Cancer Research 2228-6527 14 1 2023 02 14 44 51 Faiz Shera Sher-i-kashmir Institute of Medical Sciences, Srinagar, J&K Tahleel Shera Sher-i-kashmir Institute of Medical Sciences, Srinagar, J&K Omair Shah Sher-i-kashmir Institute of Medical Sciences, Srinagar, J&K Irfan Robbani Sher-i-kashmir Institute of Medical Sciences, Srinagar, J&K Naseer Choh Sher-i-kashmir Institute of Medical Sciences, Srinagar, J&K Tariq Gojwari Sher-i-kashmir Institute of Medical Sciences, Srinagar, J&K Abdul Dar Sher-i-kashmir Institute of Medical Sciences, Srinagar, J&K Sonaullah Shah Sher-i-kashmir Institute of Medical Sciences, Srinagar, J&K 2022 07 20 2023 01 11 Respected Editors, The purpose of this study was to evaluate the incidence and risk factors of post-procedure pneumothorax after CT guided transthoracic lung biopsy. This study has not been published or sent for publication in any other journal by any of the authors.While many studies have evaluated this topic most of them are univariate analysis. This study utilizes multivariate logistic regression analysis to identify which of the risk factors are independent predictors of pneumothorax. Moreover this study has identified a novel risk factor of post procedure pneumothorax.-the  lateral position of the patient during biopsy. This risk factor has scarcely been mentioned in literature previously and would definitely add to the current knowledge on the topic. Thank You. https://bccr.tums.ac.ir/index.php/bccrj/article/view/436