Tehran University of Medical Sciences Basic & Clinical Cancer Research 2228-6527 13 4 2023 01 18 320 335 Abuzar Shakeri Department of Nuclear Engineering, Bushehr Branch, Islamic Azad University, Bushehr, Iran Ebrahim Heidari Department of Sciences, Bushehr Branch, Islamic Azad University, Bushehr, Iran Seyedeh Nasrin Hosseini Motlagh Department of Physics, Shiraz Branch, Islamic Azad University, Shiraz, Iran Hamid Reza Vanaei Department of Sciences, Bushehr Branch, Islamic Azad University, Bushehr, Iran 2021 04 17 2022 12 18 Fluorine 18-deoxyglucose is often used in Positron Emission Tomography devices. Positron Emission Tomography imaging is one of the useful tools which is used for cancer detection and its management. Positron Emission Tomography growth is limited due to problems that depend on the production of Fluorine-18. Imaging results are strongly depending on the information of nuclear reaction cross-section data. This study is presented to calculate different quantities such as stopping power, CSDA range, and simulated and distributed absorbed dose of Fluorine-18 in water. In order to access these goals, we use Geant4/Gate7 simulation and the theoretical Bethe-Bloch model. The results of this simulation and the theoretical model presented are in good agreement with each other. The important point of this paper is the presentation of a theoretical approach in order to the production of Fluorine-18 using protons generated through the main D(d;p) Tand side 3He(d;p)4He nuclear fusion reaction in which uses Helium-3 is catalyzed. https://bccr.tums.ac.ir/index.php/bccrj/article/view/382