Tehran University of Medical Sciences Basic & Clinical Cancer Research 2228-6527 6 4 2014 12 15 21 25 EN Habibollah Mahmoodzade Department of Surgical Oncology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran Abdolreza Sheikhrezai Department of Neurosurgery, Imam Khomeini Medical Center, Tehran, Iran farhad Samiei Department of Radiotherapy, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran Afsaneh Alikhassi Department of Radiology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran Fazel Elahi Department of Medical Oncology, Cancer Institute , Tehran University of Medical Sciences, Tehran, Iran Fereshteh Ensani Department of Pathology, Cancer Institute , Tehran University of Medical Sciences, Tehran, Iran Afshin Abdi-e-rad Department of Pathology, Cancer Institute , Tehran University of Medical Sciences, Tehran, Iran Sina Izadyar Imam Khomeini Medical Center, Tehran University of Medical Sciences, Tehran, Iran Ramesh Omranipur Department of Surgical Oncology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran Mohammad Reza Mir Department of Surgical Oncology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran Zahra Sedighi Cancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran Siamak Shariat-e-torbaghan Department of Pathology, Cancer Institute , Tehran University of Medical Sciences, Tehran, Iran Mohammad-Ali Mohagheghi Department of Surgical Oncology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran 2015 11 29 2015 11 29 A 38 years old male worker presented with an advanced left side retroperitoneal mass, with metastatic involvement of 11th Thoracic Vertebra (T11) and resultant paraparesia and paresthesia . The histopathologic examination and immunohistochemical analysis confirmed the diagnosis of paraganglioma. Decompression laminectomy and fixation of involved vertebra resulted to considerable symptomatic relief. Due to unresectability at presentation, chemotherapy with palliative intent performed, and resulted to mild response.  Palliative debulking performed after chemotherapy and resulted to better quality of patient's life during next 8 months. Remaining  mass at pelvic area increased in size and patient received    (131)I-MIBG therapy, 8 months post-operatively. A second debulking surgery, as well as other palliative measures will be considered for future.  https://bccr.tums.ac.ir/index.php/bccrj/article/view/175 https://bccr.tums.ac.ir/index.php/bccrj/article/download/175/187